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Bazedoxifene Acetate; Estrogens, Conjugated

Sold as DUAVEE · given by oral

Within a year until it comes off patent
7 mo
Until anyone may copy it
Protection runs to 2027-03-10
6
Trials running now
55 registered in total
In routine use
Furthest stage reached
already in routine clinical use
3
Organisations running trials
lead sponsors on record
01

Who owns it, and until when

Wyeth Pharmaceuticals Llc
Approval holder
the only company permitted to sell it today
2027-03
Last patent expires
latest patent filed against this product
none listed
FDA exclusivity ends
a separate protection granted at approval

Whichever date falls later is when other manufacturers may apply to sell copies. Price typically falls steeply within a year of that point, and with it any company's ability to recover the cost of new research on the molecule. That is when it becomes a candidate for the ledger on the first tab.

02

What it is being tested for

OsteoporosisMenopausePostmenopause
03

Who is paying for the research

Wyeth is now a wholly owned subsid
Company
17
Pfizer
Company
9
Alvogen Korea
Company
2

Who funds the trials matters after protection lapses. Company-funded work usually stops once exclusivity ends; university, hospital and government-funded work does not, and is the research most likely to continue on this molecule afterwards.

04

The trials themselves

NCT04478305Phase 12024 · 30 people · recruiting now
Affect of Duavive on Mood & Anxiety Symptoms

Expiry dates are what the patent holder has filed; litigation, paediatric extensions and settlements routinely move them, so read these as the earliest plausible date rather than a schedule. Not medical advice.

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