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Cabozantinib S-Malate

Sold as CABOMETYX, COMETRIQ · given by oral

Five to ten years until it comes off patent
6.9 yr
Until anyone may copy it
Protection runs to 2033-07-09
23
Trials running now
45 registered in total
Phase 3
Furthest stage reached
large trials measuring benefit
3
Organisations running trials
lead sponsors on record
01

Who owns it, and until when

Exelixis Inc
Approval holder
the only company permitted to sell it today
2033-07
Last patent expires
latest patent filed against this product
2032-03
FDA exclusivity ends
a separate protection granted at approval

Whichever date falls later is when other manufacturers may apply to sell copies. Price typically falls steeply within a year of that point, and with it any company's ability to recover the cost of new research on the molecule. That is when it becomes a candidate for the ledger on the first tab.

02

What it is being tested for

Stage IV Renal Cell Cancer AJCC v8Advanced Renal Cell CarcinomaMetastatic Papillary Renal Cell Carcin
03

Who is paying for the research

National Cancer Institute (NCI)
US government
32
University of Washington
University or hospital
3
M.D. Anderson Cancer Center
University or hospital
3

Who funds the trials matters after protection lapses. Company-funded work usually stops once exclusivity ends; university, hospital and government-funded work does not, and is the research most likely to continue on this molecule afterwards.

04

The trials themselves

NCT06811116Phase 12025 · 92 people · recruiting now
Testing the Addition of an Anti-cancer Drug,

Expiry dates are what the patent holder has filed; litigation, paediatric extensions and settlements routinely move them, so read these as the earliest plausible date rather than a schedule. Not medical advice.

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