Crizotinib

Sold as XALKORI · given by oral

Three to five years until it comes off patent
3.2 yr
Until anyone may copy it
Protection runs to 2029-11-06
13
Trials running now
172 registered in total
In routine use
Furthest stage reached
already in routine clinical use
3
Organisations running trials
lead sponsors on record
01

Who owns it, and until when

Pf Prism Cv
Approval holder
the only company permitted to sell it today
2029-11
Last patent expires
latest patent filed against this product
2029-07
FDA exclusivity ends
a separate protection granted at approval

Whichever date falls later is when other manufacturers may apply to sell copies. Price typically falls steeply within a year of that point, and with it any company's ability to recover the cost of new research on the molecule. That is when it becomes a candidate for the ledger on the first tab.

02

What it is being tested for

Carcinoma, Non-Small-Cell LungNon-small Cell Lung CancerNon-Small Cell Lung Cancer
03

Who is paying for the research

Pfizer
Company
16
National Cancer Institute (NCI)
US government
6
Hoffmann-La Roche
Company
4

Who funds the trials matters after protection lapses. Company-funded work usually stops once exclusivity ends; university, hospital and government-funded work does not, and is the research most likely to continue on this molecule afterwards.

04

The trials themselves

NCT07538973Phase 12026 · 24 people · not yet recruiting
A Clinical Study to Evaluate the Pharmacokin

Expiry dates are what the patent holder has filed; litigation, paediatric extensions and settlements routinely move them, so read these as the earliest plausible date rather than a schedule. Not medical advice.

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