← The patent line

Donidalorsen Sodium

Sold as DAWNZERA (AUTOINJECTOR) · given by subcutaneous

Five to ten years until it comes off patent
8.7 yr
Until anyone may copy it
Protection runs to 2035-05-01
2
Trials running now
7 registered in total
Phase 3
Furthest stage reached
large trials measuring benefit
1
Organisations running trials
lead sponsors on record
01

Who owns it, and until when

Ionis Pharmaceuticals Inc
Approval holder
the only company permitted to sell it today
2035-05
Last patent expires
latest patent filed against this product
2032-08
FDA exclusivity ends
a separate protection granted at approval

Whichever date falls later is when other manufacturers may apply to sell copies. Price typically falls steeply within a year of that point, and with it any company's ability to recover the cost of new research on the molecule. That is when it becomes a candidate for the ledger on the first tab.

02

What it is being tested for

Hereditary AngioedemaHereditary Angioedema (HAE)Healthy Volunteers
03

Who is paying for the research

Ionis Pharmaceuticals, Inc.
Company
7

Who funds the trials matters after protection lapses. Company-funded work usually stops once exclusivity ends; university, hospital and government-funded work does not, and is the research most likely to continue on this molecule afterwards.

04

The trials themselves

NCT07298447Phase 32026 · 20 people · recruiting now
Donidalorsen Treatment in Children With Here

Expiry dates are what the patent holder has filed; litigation, paediatric extensions and settlements routinely move them, so read these as the earliest plausible date rather than a schedule. Not medical advice.

← Back to the patent line