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Dordaviprone Hydrochloride

Sold as MODEYSO · given by oral

Ten years or more until it comes off patent
10.5 yr
Until anyone may copy it
Protection runs to 2037-01-30
3
Trials running now
10 registered in total
Phase 3
Furthest stage reached
large trials measuring benefit
3
Organisations running trials
lead sponsors on record
01

Who owns it, and until when

Chimerix Inc
Approval holder
the only company permitted to sell it today
2037-01
Last patent expires
latest patent filed against this product
2032-08
FDA exclusivity ends
a separate protection granted at approval

Whichever date falls later is when other manufacturers may apply to sell copies. Price typically falls steeply within a year of that point, and with it any company's ability to recover the cost of new research on the molecule. That is when it becomes a candidate for the ledger on the first tab.

02

What it is being tested for

GliomaDiffuse Intrinsic Pontine GliomaH3 K27M
03

Who is paying for the research

Jazz Pharmaceuticals
Company
6
University of Nebraska
University or hospital
2
Gustave Roussy, Cancer Campus, Gra
University or hospital
1

Who funds the trials matters after protection lapses. Company-funded work usually stops once exclusivity ends; university, hospital and government-funded work does not, and is the research most likely to continue on this molecule afterwards.

04

The trials themselves

NCT06012929Phase 22026 · withdrawn
A Study of ONC201 for Refractory Meningioma

Expiry dates are what the patent holder has filed; litigation, paediatric extensions and settlements routinely move them, so read these as the earliest plausible date rather than a schedule. Not medical advice.

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