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Enasidenib Mesylate

Sold as IDHIFA · given by oral

Five to ten years until it comes off patent
8.1 yr
Until anyone may copy it
Protection runs to 2034-09-16
24
Trials running now
49 registered in total
Phase 3
Furthest stage reached
large trials measuring benefit
3
Organisations running trials
lead sponsors on record
01

Who owns it, and until when

Bristol Myers Squibb
Approval holder
the only company permitted to sell it today
2034-09
Last patent expires
latest patent filed against this product
none listed
FDA exclusivity ends
a separate protection granted at approval

Whichever date falls later is when other manufacturers may apply to sell copies. Price typically falls steeply within a year of that point, and with it any company's ability to recover the cost of new research on the molecule. That is when it becomes a candidate for the ledger on the first tab.

02

What it is being tested for

Acute Myeloid LeukemiaRecurrent Acute Myeloid LeukemiaIDH2 Gene Mutation
03

Who is paying for the research

Celgene
Company
11
M.D. Anderson Cancer Center
University or hospital
4
National Cancer Institute (NCI)
US government
4

Who funds the trials matters after protection lapses. Company-funded work usually stops once exclusivity ends; university, hospital and government-funded work does not, and is the research most likely to continue on this molecule afterwards.

04

The trials themselves

NCT06577441Phase 22025 · 54 people · recruiting now
Testing the Addition of an IDH2 Inhibitor, E

Expiry dates are what the patent holder has filed; litigation, paediatric extensions and settlements routinely move them, so read these as the earliest plausible date rather than a schedule. Not medical advice.

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