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Maralixibat Chloride

Sold as LIVMARLI · given by oral

Ten years or more until it comes off patent
17.1 yr
Until anyone may copy it
Protection runs to 2043-10-05
0
Trials running now
5 registered in total
Phase 3
Furthest stage reached
large trials measuring benefit
2
Organisations running trials
lead sponsors on record
01

Who owns it, and until when

Mirum Pharmaceuticals Inc
Approval holder
the only company permitted to sell it today
2043-10
Last patent expires
latest patent filed against this product
2031-07
FDA exclusivity ends
a separate protection granted at approval

Whichever date falls later is when other manufacturers may apply to sell copies. Price typically falls steeply within a year of that point, and with it any company's ability to recover the cost of new research on the molecule. That is when it becomes a candidate for the ledger on the first tab.

02

What it is being tested for

Cholestatic Liver DiseaseAlagille SyndromeProgressive Familial Intrahepatic Chol
03

Who is paying for the research

Mirum Pharmaceuticals, Inc.
Company
3
Takeda
Company
2

Who funds the trials matters after protection lapses. Company-funded work usually stops once exclusivity ends; university, hospital and government-funded work does not, and is the research most likely to continue on this molecule afterwards.

04

The trials themselves

NCT05543174Phase 32023 · 7 people · completed
A Study of TAK-625 for the Treatment of Alag

Expiry dates are what the patent holder has filed; litigation, paediatric extensions and settlements routinely move them, so read these as the earliest plausible date rather than a schedule. Not medical advice.

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