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Mitapivat Sulfate

Sold as AQVESME, PYRUKYND · given by oral

Ten years or more until it comes off patent
15.0 yr
Until anyone may copy it
Protection runs to 2041-07-31
14
Trials running now
30 registered in total
In routine use
Furthest stage reached
already in routine clinical use
3
Organisations running trials
lead sponsors on record
01

Who owns it, and until when

Agios Pharmaceuticals Inc
Approval holder
the only company permitted to sell it today
2041-07
Last patent expires
latest patent filed against this product
2032-12
FDA exclusivity ends
a separate protection granted at approval

Whichever date falls later is when other manufacturers may apply to sell copies. Price typically falls steeply within a year of that point, and with it any company's ability to recover the cost of new research on the molecule. That is when it becomes a candidate for the ledger on the first tab.

02

What it is being tested for

Sickle Cell DiseasePyruvate Kinase DeficiencyHealthy Volunteers
03

Who is paying for the research

Agios Pharmaceuticals, Inc.
Company
25
National Heart, Lung, and Blood In
US government
2
University Health Network, Toronto
University or hospital
1

Who funds the trials matters after protection lapses. Company-funded work usually stops once exclusivity ends; university, hospital and government-funded work does not, and is the research most likely to continue on this molecule afterwards.

04

The trials themselves

NCT07517133Phase 32026 · 45 people · recruiting now
A Study to Investigate the Efficacy, Pharmac

Expiry dates are what the patent holder has filed; litigation, paediatric extensions and settlements routinely move them, so read these as the earliest plausible date rather than a schedule. Not medical advice.

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