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Motixafortide Acetate

Sold as APHEXDA · given by subcutaneous

Ten years or more until it comes off patent
15.4 yr
Until anyone may copy it
Protection runs to 2041-12-29
6
Trials running now
10 registered in total
In routine use
Furthest stage reached
already in routine clinical use
3
Organisations running trials
lead sponsors on record
01

Who owns it, and until when

Ayrmid Pharma Ltd
Approval holder
the only company permitted to sell it today
2041-12
Last patent expires
latest patent filed against this product
2030-09
FDA exclusivity ends
a separate protection granted at approval

Whichever date falls later is when other manufacturers may apply to sell copies. Price typically falls steeply within a year of that point, and with it any company's ability to recover the cost of new research on the molecule. That is when it becomes a candidate for the ledger on the first tab.

02

What it is being tested for

Multiple MyelomaSickle Cell DiseaseAcute Myeloid Leukemia
03

Who is paying for the research

Washington University School of Me
University or hospital
3
St. Jude Children's Research Hospi
University or hospital
2
BioLineRx, Ltd.
Company
2

Who funds the trials matters after protection lapses. Company-funded work usually stops once exclusivity ends; university, hospital and government-funded work does not, and is the research most likely to continue on this molecule afterwards.

04

The trials themselves

NCT07392970Phase 22026 · 10 people · recruiting now
Motixafortide for MRD Sensitization in AML

Expiry dates are what the patent holder has filed; litigation, paediatric extensions and settlements routinely move them, so read these as the earliest plausible date rather than a schedule. Not medical advice.

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