Palovarotene

Sold as SOHONOS · given by oral

Ten years or more until it comes off patent
10.8 yr
Until anyone may copy it
Protection runs to 2037-06-08
1
Trials running now
12 registered in total
Phase 3
Furthest stage reached
large trials measuring benefit
2
Organisations running trials
lead sponsors on record
01

Who owns it, and until when

Ipsen Biopharmaceuticals Inc
Approval holder
the only company permitted to sell it today
2037-06
Last patent expires
latest patent filed against this product
2030-08
FDA exclusivity ends
a separate protection granted at approval

Whichever date falls later is when other manufacturers may apply to sell copies. Price typically falls steeply within a year of that point, and with it any company's ability to recover the cost of new research on the molecule. That is when it becomes a candidate for the ledger on the first tab.

02

What it is being tested for

Fibrodysplasia Ossificans ProgressivaFibrodysplasia Ossificans Progressiva Hepatic Impairment
03

Who is paying for the research

Clementia Pharmaceuticals Inc.
Company
9
Ipsen
Company
3

Who funds the trials matters after protection lapses. Company-funded work usually stops once exclusivity ends; university, hospital and government-funded work does not, and is the research most likely to continue on this molecule afterwards.

04

The trials themselves

NCT06908954Phase 12025 · 31 people · completed
A Study of the Blood Levels of Palovarotene

Expiry dates are what the patent holder has filed; litigation, paediatric extensions and settlements routinely move them, so read these as the earliest plausible date rather than a schedule. Not medical advice.

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