Selinexor

Sold as XPOVIO · given by oral

Five to ten years until it comes off patent
9.0 yr
Until anyone may copy it
Protection runs to 2035-08-14
31
Trials running now
205 registered in total
In routine use
Furthest stage reached
already in routine clinical use
3
Organisations running trials
lead sponsors on record
01

Who owns it, and until when

Karyopharm Therapeutics Inc
Approval holder
the only company permitted to sell it today
2035-08
Last patent expires
latest patent filed against this product
2027-12
FDA exclusivity ends
a separate protection granted at approval

Whichever date falls later is when other manufacturers may apply to sell copies. Price typically falls steeply within a year of that point, and with it any company's ability to recover the cost of new research on the molecule. That is when it becomes a candidate for the ledger on the first tab.

02

What it is being tested for

Multiple MyelomaAcute Myeloid LeukemiaPeripheral T-cell Lymphoma (PTCL)
03

Who is paying for the research

Karyopharm Therapeutics Inc
Company
8
Ruijin Hospital
University or hospital
7
Tianjin Medical University Cancer
University or hospital
3

Who funds the trials matters after protection lapses. Company-funded work usually stops once exclusivity ends; university, hospital and government-funded work does not, and is the research most likely to continue on this molecule afterwards.

04

The trials themselves

NCT07479979Phase 12026 · 62 people · recruiting now
Study of Selinexor With Carfilzomib, Isatuxi

Expiry dates are what the patent holder has filed; litigation, paediatric extensions and settlements routinely move them, so read these as the earliest plausible date rather than a schedule. Not medical advice.

← Back to the patent line