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Selumetinib Sulfate

Sold as KOSELUGO · given by oral

Five to ten years until it comes off patent
6.3 yr
Until anyone may copy it
Protection runs to 2032-11-19
18
Trials running now
141 registered in total
Phase 3
Furthest stage reached
large trials measuring benefit
3
Organisations running trials
lead sponsors on record
01

Who owns it, and until when

Astrazeneca Pharmaceuticals Lp
Approval holder
the only company permitted to sell it today
2029-03
Last patent expires
latest patent filed against this product
2032-11
FDA exclusivity ends
a separate protection granted at approval

Whichever date falls later is when other manufacturers may apply to sell copies. Price typically falls steeply within a year of that point, and with it any company's ability to recover the cost of new research on the molecule. That is when it becomes a candidate for the ledger on the first tab.

02

What it is being tested for

Neurofibromatosis 1MelanomaSolid Tumours
03

Who is paying for the research

National Cancer Institute (NCI)
US government
16
AstraZeneca
Company
14
M.D. Anderson Cancer Center
University or hospital
4

Who funds the trials matters after protection lapses. Company-funded work usually stops once exclusivity ends; university, hospital and government-funded work does not, and is the research most likely to continue on this molecule afterwards.

04

The trials themselves

NCT05253131Phase 22026 · 41 people · not yet recruiting
Trial of Selumetinib and Bromodomain Inhibit

Expiry dates are what the patent holder has filed; litigation, paediatric extensions and settlements routinely move them, so read these as the earliest plausible date rather than a schedule. Not medical advice.

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