Tovorafenib

Sold as OJEMDA · given by oral

Five to ten years until it comes off patent
8.8 yr
Until anyone may copy it
Protection runs to 2035-06-23
9
Trials running now
16 registered in total
Phase 3
Furthest stage reached
large trials measuring benefit
3
Organisations running trials
lead sponsors on record
01

Who owns it, and until when

Day One Biopharmaceuticals Inc
Approval holder
the only company permitted to sell it today
2035-06
Last patent expires
latest patent filed against this product
2031-04
FDA exclusivity ends
a separate protection granted at approval

Whichever date falls later is when other manufacturers may apply to sell copies. Price typically falls steeply within a year of that point, and with it any company's ability to recover the cost of new research on the molecule. That is when it becomes a candidate for the ledger on the first tab.

02

What it is being tested for

Low-grade GliomaMelanomaSolid Tumor
03

Who is paying for the research

Day One Biopharmaceuticals, Inc.
Company
5
Millennium Pharmaceuticals, Inc.
Company
3
National Cancer Institute (NCI)
US government
2

Who funds the trials matters after protection lapses. Company-funded work usually stops once exclusivity ends; university, hospital and government-funded work does not, and is the research most likely to continue on this molecule afterwards.

04

The trials themselves

NCT07206849Phase 22026 · 79 people · not yet recruiting
Study of Tovorafenib in High-Grade Glioma an

Expiry dates are what the patent holder has filed; litigation, paediatric extensions and settlements routinely move them, so read these as the earliest plausible date rather than a schedule. Not medical advice.

← Back to the patent line